“Copernicus’ unique, non-viral nanoparticle formulation is designed to safely and effectively deliver and express therapeutic genes and siRNAs to sites of human disease, including the brain, eye, and lung,” said Mark J. Cooper, senior VP of Science and Medical Affairs at Copernicus. “We are most encouraged by the positive treatment results of Parkinson’s disease rats treated with DNA nanoparticles containing the GDNF gene. Copernicus has developed proprietary expression elements that achieve long term gene expression in various tissues, and sustained expression of GDNF in the rat brain will lead to further IND-track studies for a phase I human clinical trial in Parkinson’s disease subjects.”
“I have long maintained that it is important for UK researchers to reach out and partner with industry leaders,” said UK President Lee T. Todd, Jr. “Dr. Yurek’s research collaboration with Copernicus Therapeutics is a perfect example of how we can leverage the innovation and discovery in our labs to add value to private sector companies. And I hope the partnership will lead to some important breakthroughs in our on-going battle against Parkinson’s disease.”
Funding for this project has been provided by The Michael J. Fox Foundation for Parkinson’s Research.
About Copernicus
Copernicus Therapeutics, Inc., a privately held biotechnology company, is dedicated to delivering the promise of nucleic acid therapeutics. The same technology that delivers the GDNF gene to Parkinson’s disease patients can be applied to treating other brain disorders, retinitis pigmentosa and other ocular diseases, and the lung manifestations of cystic fibrosis. The Copernicus multi-component delivery platform and expression systems can be used to develop nucleic acid therapies for numerous human diseases. Additional information about Copernicus is available at http://www.copernicustherapeutics.com.
Copernicus Therapeutics, Inc.
Mark J. Cooper, M.D., 216-231-0227 x 23
Sr. V.P. of Science and Medical Affairs
mcooper@cgsys.com
or
Robert C. Moen, M.D., Ph.D., 216-231-0227 x26
President & CEO
rmoen@cgsys.com
1 comment:
I am a 51 year old female that just found out I have Motor Neuron Disease Parkinson's about a year and half, but I have been having signs of it for years, tremors, depression, body weakness. ECT. I honestly don't think my doctor was reading the signs because of my gender and age. A few years ago I had my shoulder lock up on me and I was sent to a P.T since x-rays didn't show any physical damage. My shaking was getting worse and I began falling. Only when my speech became so bad that it brought concern to my dentist was Parkinson's even considered. He phoned my doctor with his concerns about my shaking and balance problems. By this time I was forgoing shots in the back of my neck for back and neck pain to which once again I was sent to a P.T (although x-rays showed no damage) I was told I had a few spurs which were most likely causing the pain. Here I was feeling like my whole body was falling apart and doctor could not find anything wrong, maybe in was all in my head? My doctor even seemed annoyed with me and things just kept progressing and I just kept it to myself, why bother going through testing and them finding nothing? Well, it was after my second P.T called my doctor about the weakness in my legs and arms, by this time I have developed a gait in my walk and I fell more frequently. Only then did my doctor send me to a specialist and it was found that I had Parkinson's, and that I have had it for awhile. I think because I was a woman that my signs and symptoms weren't taken seriously and therefor left untreated for so long,I was taking pramipexole dihydrochloride three times daily, I Was on carbidopa levodopa but only lasted 90 minutes then wore off.I found that none of the current medications worked effective for me.I got tired of using those medication so I decided to apply natural herbs formula that was prescribed to me by my second P.T, i purchase the herbal formula from totalcureherbsfoundation. com, There has been huge progression ever since I start the treatment plan which will last for 15 weeks usage.all the symptoms and sign has begin to disappear .
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